Early Stage Drug Development Company

We’re development of Organ On-Chip System to which real human blood is applied

and drug application efficacy test and evaluation company

Research cooperation system and structure

Importance of R&D

  • Etomidate, propofol and opioid anesthetics classified as propofols are used to treat insomnia, and they cause mental dependence and addiction through misuse and habitual administration for the purpose of recovery from fatigue and hallucinations.
  • In December 2016, the U.S. Food and Drug Administration (FDA) stated in its Drug Safety Communication (DSC) that “repeated or prolonged use of general anesthetics and sedatives during surgery or procedures in children under 3 years of age or during the trimester of pregnancy may have an effect.” In particular, it warned that the volatile anesthesia of inhaled anesthetics could create potential neurotoxicity problems. Therefore, additional high-quality studies of the effects of repeated and prolonged anesthetic exposure in children are needed.
  • In the “Analysis of anesthesia-related medical disputes between 2009 and 2014” report by Samsung Seoul Hospital, number of criminal charges due to anesthesia-related accidents is 105(82 deaths, 16 permanent disabilities, and 7 brain damage or spinal paralysis, etc.). Among them, case by propofol was the most with 35 cases.

Importance of R&D

  • Tryptamine
    (Potential therapeutic targets
    for neuropsychiatric disorders)

  • Sumatriptan
    (Migraines and Cluster headaches)

  • Serotonin
    (Bipolar disorder, Depression,
    Obesity, Smoking cessation)

  • Melatonin
    (Sleeping pills, Neuroleptics, Dystonia)

  • Psilocybin
    (Depression, Alcoholism, Drug addiction)